Dr.Sajjad Gharaghani
Sajjad Gharaghani, Ph.D. Assistant Professor Tel: (+98)-21-88993950 Fax: (+98)-21-66404680 E-mail: s.gharaghani@ut.ac.ir Website: http://lbd.ut.ac.ir |
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CV
- Personal Records
- Research Interests and Project
- Publications
- Scientific Activity
- Honors And Awards
- Students
- Course
Personal Records | Education | |||
Name: Sajjad Gharaghani Date of Birth:23 Jan 1982 Place of Birth: Semirom, Iran Marital Status: Married, 1 Children Appointment: Assistant Professor Office Address: Institute of Biochemistry and Biophysics, Department of Bioinformatics, Laboratory of Bioinformatics and Drug Design (LBD) University of Tehran P.O.Box 1417614335 Tehran, Iran Telephone: 0098 21 61113451 Fax: 0098 21 66956977 E-Mail: s.gharaghani@ut.ac.ir Web Site: http://lbd.ut.ac.ir/ Web Site: ibb.ut.ac.ir/gharaghani | Ph.D: From: Isfahan University of Technology, Isfahan, Iran (2013) Major: Chemoinformatics Thesis: Structure-based QSAR by using homology modeling, molecular docking and molecular dynamics simulation, and multi-target fragment based drug design for human SSAO and AChE. M.Sc: From: University of Mazandaran, Babolsar, Iran (2008) Major: Analytical Chemistry (Chemometrics) Thesis: A novel QSAR model for prediction of apoptosis-inducing activity of 4-aryl-4-H-chromenes and prediction of selectivity coefficients of univalent anions for anion-selective electrode using support vector machine. |
Research interests and project
• Bioinformatics
• Pharmacoinformatics
• Systems Pharmacology
• Computational Drug Design (ligand-based, structure-based and fragment-based)
• Chemogenomics
• Chemoinformatics
• Computational Biology and Biological Networks
• Chemometrics
• Machine Learning Methods in Drug Discovery
• Quantitative Structure-Activity Relationship (QSAR)
Publications
Full International Papers
Publications in ISI Journals:
1- A Benvidi*, S Abbasi, S Gharaghani, M Dehghan Tezerjani, S Masoum, "Spectrophotometric determination of synthetic colorants using PSO–GA-ANN", Food Chemistry (2017) 220, 377-384.
International Proceedings
Sajjad Gharaghani "Bioinformatics in drug discovery" 2nd International & 14th IRANIAN Genetics Congress, University of Shahid Beheshty, 2016, Tehran, Iran. (lecture)
National Proceedings
1- Sajjad Gharaghani "Bioinformatics in drug discovery" 2nd International & 14th IRANIAN Genetics Congress, University of Shahid Beheshty, 2016, Tehran, Iran. (lecture)
2- Sajjad Gharaghani "Computational Chemogenomics: an emerging strategy for rapid target and drug discovery" 5th Iranian Biennial Chemometrics Seminar, University of Tehran, 2015, Tehran, Iran. (lecture)
3- Elmira Nazarshodeha and Sajjad Gharaghani, "Pharmacophore-based virtual screening and toxicity risk analysis for identifying novel MPS1 inhibitors" 5th Iranian Biennial Chemometrics Seminar, University of Tehran, 2015, Tehran, Iran. (poster)
4- Afsane Heidari, Mohammad H. Fatemi and Sajjad Gharaghani "Hybrid docking-QSAR methodology in prediction of HIV-1 protease inhibitory activities of some drug candidates" 5th Iranian Conference on Bioinformatics, University of Tehran, 2014, Tehran, Iran. (lecture)
5- S. Gharaghani, T. Khayamian, "A target-based QSAR study on quinolizidinone carboxylic acids as muscarinic acetylcholine positive allosteric modulators using docking, molecular dynamics simulation and least squares-support vector regression" 18th Iranian seminar of analytical chemistry, Zahedan university, 2011 (lecture)
6- Z. Hassanzadeh, S. Gharaghani, M. Saraji,T. Khayamian, "A novel QSPR model for prediction of ionization efficiency (IE) of organic compounds using least squares support vector regression" 17th Iranian seminar of analytical chemistry, Kashan university, 2010 (poster)
7- S. Gharaghani, T. Khayamian, "A target-based QSAR study on 4-[(diethylamino)methyl]-phenol derivatives as cholinesterase inhibitors using docking, molecular dynamic simulation and least squares-support vector machine" 16th Iranian seminar of analytical chemistry, Kashan university, 2010 (lecture)
8- S. Gharaghani, T. Khayamian, F. Keshavarz, "QSAR studies on benzodiazepine classes as a selective GABAA α5 inverse agonist using Homology Modeling, Molecular Dynamic Simulation and Molecular Docking" 2th Iranian seminar of Chemometrics, Urmia university, 2009 (lecture)
9- T. Khayamian , S. Gharaghani, F. Keshavarz "Bioinformatics"16th Iranian seminar of analytical chemistry, Hamedan university, 2009 (lecture)
10- S. Gharaghani, F. Keshavarz, T. Khayamian "QSAR for Predicting Inhibitors of Cytochrome P450 2A6 Using Molecular Docking and Molecular Dynamic Simulation",16th Iranian seminar of analytical chemistry, Hamedan university, 2009 (lecture)
11- M.H.Fatemi, S.Gharaghani, "Prediction of selectivity coefficients of univalent anions for liquid ion-exchange membrane electrodes using support vector machine", Urmia university, 7th Iranian seminar of electrochemistry, 2008 (lecture)
12- M. H. Fatemi, M. Ghorbanzadeh, S. Gharaghani, E. Baher, "Support vector regression based QSPR modeling of retention factor in micellar electric chromatography", 15th Iranian seminar of analytical chemistry, Shiraz university, Feb. 2007 (poster)
13- E. Baher, M. H. Fatemi, S. Gharaghani, M. Ghorbanzadeh, " Support vector regression modeling of degradability rate constant of alkenes by OH radical in atmosphere", 15th Iranian seminar of analytical chemistry, Shiraz university, Feb. 2007 (poster)
14- M.H.Fatemi, S.Gharaghani, M.Ghahramani, E.Baher, M.Ghorbanzade " QSAR Modeling of Blood-Brain Barrier Penetration Coefficients by Using Support Vector Machine", 15th Iranian seminar of analytical chemistry, Shiraz university, Feb. 2007 (poster)
15- M.H.Fatemi, S.Gharaghani, E.Baher , M.Ghorbanzade, "Prediction of Gas-Phase Degradation Rate Constant of Alkenes by NO3 Using Support Vector Regression ", 15th Iranian seminar of analytical chemistry, Shiraz university, Feb. 2007 (lecture)
Activity in Scientific Journals
Reviewer for International Journals
1-Chemical Biology and Drug Design
2-Computers in Biology and Medicine
3-Journal of Biomolecular Structure & Dynamics
4-Cellular and Molecular Bioengineering
5-Journal of Iranian Chemical Society (JICS)
6-Iranian Journal of Pharmaceutical Research
7-Iranian Journal of Chemistry and Chemical Engineering (IJCCE)
8-International Journal of Nanoscience and Nanotechnology
Activity in Scientific Societies
1) Member Iranian Bioinformatics Society (IBIS)
2) Member of Iranian Chemistry Society (ICS).
3) Member of American Chemistry Society (ACS).
Member of Conference Organizing Committee
Research Postgraduate Students Supervised
A) M.Sc Students:
1) Mr. Abdolhossein Habibzadeh Ardabili (Computer Engineering, 2015)
University of Tehran, School of Electrical and Computer Engineering,
An Approach to finding Motif in Weighted Networks
2) Ms. Farhaneh Moradi (Artificial Intelligence, 2015)
Alzahra University, Faculty of Engineering,
Discovering Compounds with Activity Cliff Property in QSAR Approach Using Machine Learning Algorithms
3) Ms. Hakime Moghadam( Computer Engineering, 2016)
University of Tehran, School of Electrical and Computer Engineering,
A novel approach to drug repositioning based on the heterogeneous data fusion
4) Ms. Sedigheh Sadat Jafarypour (Biophysics, current) University of Tehran, IBB
B)Ph.D Students
1) Ms. Soheila Shabani (Bioinformatics, current) University of Tehran, IBB
2) Mr. Farshid Shirafkan (Bioinformatics, current) University of Tehran, IBB
C)Visiting Fellows
1) Ms. Razieh Sheikhpour (Ph.D Student in Computer Engineering, Software, current) Yazd University
Course titles
• Computational Drug Design (Ph.D. Course)
• Chemoinformatics (Ph.D. Course)
• Seminar in Bioinformatics (Ph.D. Course)
• Special Topics in Computational Drug Design (Ph.D. Course)