Dr. Mojtaba Bagheri
| Mojtaba Bagheri Assistant Professor of Biochemistry Institute of Biochemistry and Biophysics (IBB), University of Tehran Tel: (+98)-21-66969255, (+98)-21-61113452 Fax: (+98)-21-66404680 E-mail: mojtabagheri@ut.ac.ir Web page: ibb.ut.ac.ir/~bagheri |
CV
- Personal Records
- Research Interests and Project
- Publications
- Scientific Activity
- Honors And Awards
- Students
- Course
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| Education | |||
| Position: Assistant Professor of Biochemistry Contact Info Peptide Chemistry Laboratory, Institute of Biochemistry and Biophysics, University of Tehran, 16 Azar Street, 1417614335 Tehran, Iran, P.O. Box: 13145-1365. E-mail: mojtabagheri@ut.ac.ir Office: Tel: (+98)-21-66969255, (+98)-21-61113452 Fax: (+98)-21-66404680 | November 2010 – January 2012 Postdoctoral Research Fellow Institute of Pharmaceutical Biotechnology / University of Saarland / Saarbrücken, Germany October 2006 – October 2010 PhD Department of Biology, Chemistry and Pharmacy / FreieUniversität Berlin / Berlin, Germany September 2002 – September 2004 MSc Department of Chemistry/ Sharif University of Technology / Tehran, Iran September 1998 – July 2002 BSc Department of Chemistry / Shiraz University / Shiraz, Iran CURRENT POSITION November 2012 – Present Assistant Professor Institute of Biochemistry and Biophysics / Department of Biochemistry, University of Tehran / Tehran, Iran |
FUNDING
June 2013 – September 2015 Institute of Biochemistry and Biophysics / Department of Biochemistry, University of Tehran / Tehran, Iran
Research Grant Funding for the project entitled: Design, Synthesis and Evaluation of Activities of Trypsin-Resistant Antimicrobial Peptides to Develop Drugs for Treatment of Infections Caused by Bacterial Superbugs, received from the Iran National Science Foundation
Publications
1. Dinh Thuy Duong, Shalini Singh, Mojtaba Bagheri, Artur Schmidtchen, and Martin Malmsten. 2016. Pronounced peptide selectivity for melanoma through tryptophan end-tagging. Scientific Reports, in revision
2. Mojtaba Bagheri, Shima Arasteh, Evan F. Haney, Robert E. W. Hancock.
2016. Tryptic stability of synthetic bactenecin derivatives is determined by the side chain length of cationic residues and the peptide conformation. Journal of Medicinal Chemistry, 59:ASAP
3. MojtabaBagheri. 2015. Cationic antimicrobial peptides (AMPs): thermodynamic characterization of peptide-lipid interactions and biological efficacy of surface-tethered peptides. ChemistryOpen, 4:389-393.
4. Saeed Yousefinejad, Mojtaba Bagheri, Ali Akbar Moosavi-Movahedi. 2015.
Quantitative sequence-activity modeling of antimicrobial hexapeptides using a segmented principal component strategy: an approach to describe and predict activities of peptide drugs containing L/D and unnatural residues. Amino Acids, 47:125-134. (# citations: 4)
5. Mojtaba Bagheri, Shima Arasteh, Evan F. Haney, and Robert E. W. Hancock.
2014. Structural and thermodynamic characterization of trypsin-resistant cathelicidin derived antimicrobial peptides. Journal of Peptide Science,
20:(S1):70–70.
6. Mojtaba Bag heri, Michael Beyermann, and Margitta Dathe. 2012. The mode of action of cationic antimicrobial peptide defines the tethering position and the efficacy of biocidal surface. Bioconjugate Chemistry, 23:66-74. (# citations: 25)
7. Mojtaba Bagheri, Sandro Keller, and Margitta Dathe. 2011. Interaction of W- substituted analogs of cyclo-RRRWFR with bacterial lipopolysaccarides: The role of aromatic cluster in antimicrobial activity. Antimicrobial Agents and Chemotherapy, 55:788−797. (# citations: 16)
8. Christof Junkes, Richard D. Harvey, Kenneth D. Bruce, Rudolf Dölling, Mojtaba Bagh eri, and Margitta Dathe. 2011. Cyclic antimicrobial R-,W-rich peptides: the role of peptide structure and E. coli inner and outer membranes in activity and the mode of action. European Biophysics Journal, 40: 515−528. (# citations: 24)
9. Mojtaba Bagh eri, Michael Beyermann, and Margitta Dathe. 2009.
Immobilization reduces the activity of surface-bound cationic antimicrobial peptides with no influence upon the activity spectrum. Antimicrobial Agents and Chemotherapy, 53:1132−1141. (# citations: 101)
10. Mojtaba Bagheri, Michael Beyermann, and Margitta Dathe. 2008. Surface- bound cationic antimicrobial peptides: The effect of immobilization upon the activity spectrum and the mode of action. Journal of Peptide Science,
14:(S1):5–5.
11. Mojtaba B agheri, Najmedin Azizi, and M. Reza Saidi. 2005. An intriguing effect of lithium perchlorate dispersed on silica gel in the bromination of aromatic compounds by N-bromosuccinimide. Canadian Journal of Chemistry,
83:146−149.(# citations: 14)
12. Firouz Matloubi Moghaddam, Hassan Zali Boeini, Mojtaba Bagheri, Peter Rüedi, and Anthony Linden. 2005. Highly efficient and versatile one-pot synthesis of new thiophenelyidene compounds. Journal of Sulfur Chemistry,
26:245−250. (# citations
1. Shima Arasteh, Mojtaba Bagheri , and Bahram Goliaei. 2014. Membrane selectivity of small cyclic antimicrobial hexapeptides studied by molecular dynamics simulations. Peptide 2014 - 33EPS Proceedings. pp. 306−307.
2. Mojtaba Bagheri. May 2013. Inhibition of Bacterial Biofilms by
Antimicrobial Peptides: Take a Glance at the Parameters Affecting the Efficacy of Surface-Tethered Antimicrobial Peptides. Proceedings of the 1st International life science conference & 12th Iran biophysical chemistry conference at Tabriz. Tabriz University of Medical Sciences (Iran). pp. 2–2.
3. Shima Arasteh, Mojtaba Bagheri, and Bahram Goliaei. May 2013.
Molecular dynamics simulation studies of antimicrobial cyclo-RRRWFW and its analogs in water and POPC bilayers. Proceedings of the 1st International life science conference & 12th Iran biophysical chemistry conference at Tabriz. Tabriz University of Medical Sciences (Iran). pp. 432–432.
4. Saeed Yousefinejad, Mojtaba Bagheri, Ali Akbar Moosavi-Movahedi.
May 2013. Quantitative sequence-activity modeling of linear hexapeptide antibiotics: an approach for the prediction and description of antifungal activitys. Proceedings of the 1st International life science conference & 12th Iran biophysical chemistry conference at Tabriz. Tabriz University of Medical Sciences (Iran). pp. 423–423.
5. Mojtaba B agheri. June 2012. Interaction of cationic peptide drugs with bacteria and lipid bilayers: short R-, W-rich hexapeptides as a case study. Proceedings of the 1st International & 11th Iran Conference on Biophysical Chemistry at Ardabil, Ardabil University of Medical Sciences (Iran). pp.
A114−A114 (Abstract # 268).
6. Mojtaba B agheri, Sandro Keller, and Margitta Dathe. February 2010.
Interactions of W-substituted cyclo-RRRWFW analogues with lipid membranes studied by isothermal titration calorimetry. Proceedings of the 12th Iberian peptide meeting at Lisbon, University of Lisbon (Portugal). pp.
50-50.
7. Mojtaba B agheri, Michael Beyermann, and Margitta Dathe. 2 008. Surface bound cationic antimicrobial peptides: The effect of immobilization upon the activity spectrum and the mode of action. Peptides 2008 - 30EPS Proceedings. pp. 208-209.
1. Mojtaba Bagheri, and Robert E. W. Hancock. 2016. High performance liquid chromatography and mass spectrometry-based design of proteolytically stable antimicrobial peptides. In Antimicrobial Peptides: Methods and Protocols; Methods in Molecular Biology, in rev ision. Ed. Hansen, P. R. The Humana Press Inc., Springer Science, New York.
2. Shima Arasteh, and Mojtaba Bagheri. 2016. Molecular dynamics simulation and analysis of the antimicrobial peptides-lipid bilayers interactions. In Antimicrobial Peptides: Methods and Protocols; Methods in Molecular Biology, in rev ision. Ed. Hansen, P. R. The Humana Press Inc., Springer Science, New York.
3. Mojtaba Ba gheri. 20 10. Synthesis and thermodynamic characterization of small cyclic antimicrobial arginine and tryptophan rich peptides with selectivity for Gram-negative bacteria.In Antimicrobial Peptides: Methods and Protocols; Methods in Molecular Biology, Vol. 618. Eds. Giuliani, A., and Rinaldi, A. C. The Humana Press Inc., Springer Science, New York. 87−109. (# citations: 3)
SUPERVISING AND MENTORING ACTIVITIES
November 2012 – Present 1 PhD /4 Master Students
Institute of Biochemistry and Biophysics / Department of Biochemistry, University of Tehran / Tehran, Iran
MEMBERSHIPS OF SCIENTIFIC SOCIETIES
September 2008 – Present Member, European Peptide Society
ORGANISATION OF SCIENTIFIC MEETINGS
18/02/2014 Symposium Chair, 1st Iranian Symposium on Biomimetic Science and Technology / Institute of Biochemistry and Biophysics / University of Tehran, number of participants 70
PRIZES AND AWARDS
June 2014 – September 2014 Pharmaceutical Physical Chemistry / Department of Pharmacy /Biomedical Centre (BMC), Uppsala University / Uppsala, Sweden
Wood-Whelan Research Fellowships, Award received from the International Union of Biochemistry and Molecular Biology (IUBMB)
December 2013 Clinical Research Centre (MD11) / National University of Singapore / Singapore
Travel Fellowship, 23rd of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) conference, Award received from FAOBMB
February 2013 Institute of Biochemistry and Biophysics / Department of Biochemistry, University of Tehran / Tehran, Iran
Kazemi Ashtiani Award, Allocated to Young Elite Faculty Members of National University, Award received from the Iran's National Elites Foundation
September 2008 ONGREX / Blue & White Conferences Oy, Helsinki, Finland Travel Fellowship, 30th European Peptide symposium, Award received from the European Peptide Society July 2002 7th Chemistry Olympiad of University Students, 23-26
July 2002, Ardabil, Iran Recipient of the Gold Medal, Award received from the National Organization for Educational esting
September 2004 – September 2005 Department of Chemistry/ Sharif University of
Technology / Tehran, Iran
Fellowships for outstanding research student, Award received from Sharif University of Technology
TEACHING ACTIVITIES
September 2013 – Present Full-time course teaching–Structures and Functions of Peptides and Peptidomimetics, University of Tehran / Institute of Biochemistry and Biophysics /Tehran, Iran
February 2014 – Present Part-time course teaching–Methods in Biochemistry; NMR, University of Tehran / Institute of Biochemistry and Biophysics / Tehran, Iran
February 2016 – Present Full-time course teaching – Biophysics, University of Tehran / Faculty of Science / Department of Biology / Tehran, Iran