Masoumeh firouzi-Sheshtamad, Ph.D.
Tel: +98-21-6696-9259, 61113374
E-mail: firouzi
@ut.ac.ir                    

 

                                                                                                                                                                            

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Personal Records                                                

 

Education

 

 

Name: Masoumeh Firouzi-Sheshtamad   
Date of Birth: 1956          
Place of Birth: Sabzevar, Iran             
Marital Status: Married
Office Address: Institute of Biochemistry and Biophysics,  
University of Tehran P.O.Box 13145-1384 Tehran,Iran    
Telephone: 0098 21 61113374 
Fax: 0098 21 66404680           
E-Mail: firouzi@ut.ac.ir
Web Site: www.ut.ac.ir/~firouzi
 
 
 
 
 
 
 
 

 

 
2006-2011   PhD in Molecular Genetics, National Research Center for Biotechnology and Genetic Engineering, Tehran, Iran.
1977-1980   MSc in Molecular and cellular Biology (Biochemistry), Institute of Biochemistry and Biophysics, University of Tehran, Tehran,Iran.
 
Appointments
1987-Present   Director of Tissue Repair Lab, Institute of Biochemistry and Biophysics, University of Tehran,Tehran, Iran.
1987-1991      Member of Research and Education Council, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
 
Iran Patent 42055
2007    New technique of Schwann Cell Culture without Using of Adhesion and Growth Factors to Use in Cell Therapy in Different Human Nerve Diseases, Firouzi M., Iran Patent 42055.
2013    pain

 

 

 
Skills
  • Surgical Techniques: Access to Rat's spinal canal  and Sciatic nerve for in vivo studies.
  • Histology & Staining: frozen section, staining CNS tissue by Nissl and enzymatic (AchE and BuchE) methods.
  • Culture: Preparative culture of Human's Schwann cell from peripheral nerve of amputated foot; Preparing Culture of Pure cells of Rat's Central and peripheral Nervous System including Schwann cell, Astrocyte, Oligodendrocyte, Microglia and Hippocampal Neurons; Culture of Dorsal Root of Chick's Embryo.
  • Electrophoresis
  • Chromatography
  • Spectroscopy
 
 
Projects
  • 2005-2007 Effects of Schwann Cell Transplantation in Patients with Spinal Cord Injury: Sensorimotor and Magnetic Resonance Imaging Evaluations, Supported by Research Affair of Tehran University of Medical Sciences, Tehran, Iran.
  • 2004-2005 Effects of Subarachnoid Schwann Cell Transplantation on Rat Spinal Cord Injury, Supported by Research Affair of University of Tehran, Tehran, Iran.
  • 2004-2005 Effects of Subarachnoid Schwann Cell Transplantation on Irreversible Spinal Cord Injury in Rat by The Means of Electron Micrograph and Immunohistochemistry, Supported by Research Affair of Tehran University of Medical Sciences, Tehran, Iran.
  • 2002-2003 Isolation and Culture of Purified Microglia Cells Derived from Cortex of Newborn Rates, Supported by Research Affair of University of Tehran, Tehran, Iran.
  • 2001-2003 Activating and Mitotic Effect of Colony Stimulating Factor, Supported by Research Affair of University of Tehran, Tehran, Iran.
  • 2001-2003 Keratinocyte Culture from Hair Follicles and Synthetic Skin Preparation, Supported by Research Affair of University of Tehran, Tehran, Iran.
  • 2000-2001 Astrocyte Culture and Purification, Supported by Research Affair of University of Tehran, Tehran, Iran.
  • 2000-2002 Aspirin Effects on Peripheral Nervous System, Supported by Research Affair of University of Tehran, Tehran, Iran.
  • 1998-1999 Rat's Hippocampal Cell Culture and Purification, Supported by Research Affair of University of Tehran, Tehran, Iran.
  • 1998-1999 Schwann Cell Culture and Purification, Supported by Research Affair of University of Tehran, Tehran, Iran.
  • 1997-1998 Application of Histochemical Techniques in Peripheral Nerve Sensory-Motor Fiber Identification: A Rapid Method. Supported by Research Affair of University of Tehran, Tehran, Iran.
  • 1993-1994 Effects of Nerve Growth Factor on Nerve Regeneration: invivo and invitro Study, Supported by Research Affair of University of Tehran, Tehran, Iran.

Publications Publications

 
International Publications
  • Zadegan SA, Firouzi M, Nabian MH, Zanjani LO, Ashtiani AM, Kamrani RS. Two-Stage Nerve Graft in Severe Scar: A Time-Course Study in a Rat Model. The Archives of Bone and Joint Surgery. 2015;3(2):82-7
  • Zadegan SA, Firouzi M, Nabian MH, Zanjani LO, Kamrani RS. Two-Stage Nerve Graft Using a Silicone Tube. Frontiers in surgery. 2015;2
  • Khosroshahi ME, Hassannejad Z, Firouzi M, Arshi AR. Nanoshell-mediated targeted photothermal therapy of HER2 human breast cancer cells using pulsed and continuous wave lasers: an in vitro study. Lasers in medical science. 2015;30(7):1913-22
  • Hassannejad Z, Khosroshahi M, Firouzi M. Fabrication and Characterization of Magnetoplasmonic Liposome Carriers. Nanosci Technol. 2014;1(2):1-9
  • Zaznjani LO, Firouzi M, Nabian M-H, Nategh M, Rahimi-Movaghar V, Kamrani RS. Comparison and Evaluation of Current Animal Models for Perineural Scar Formation in Rat. Iranian journal of basic medical sciences. 2013;16(7):886.
  • Jazjayeri SB, Firouzi M, Zadegan SA, Saeedi N, Pirouz E, Nategh M, et al. The effect of timing of decompression on neurologic recovery and histopathologic findings after spinal cord compression in a rat model. Journal of Injury and Violence Research. 2012;4(3 Suppl 1).
  • Hooshang Saberi, Masoumeh Firouzi, Zohreh Habibi, Pouria Moshayedi, Hamid Reza Aghayan, Babak Arjmand, Kazem Hosseini, Hassan Emami Razavi, Mir Saeed Yekaninejad, Safety of intramedullary Schwann cell transplantation for postrehabilitation spinal cord injuries: 2-year follow-up of 33 cases, Journal of neurosurgery. Spine. 07/2011Masoumeh Firouzi, Farzaneh Sabouni, Abdolkhaleg Deezagi, Zahra Hassannejad Pirbasti, Fatemeh Poorrajab , Vafa Rahimi-Movaghar. Schwann cell apoptosis  and p75NTR siRNA. Iran J Allergy Asthema Immnul, March 2011;10 (1):53-59
  • Mohammad Hosein Nabian, Mehdi Nadji-Tehrani ,Leila Oryadi Zanjani ,Reza Shahryar Kamrani,Vafa Rahimi-Movaghar and Masoumeh Firouzi, Effect of Bilateral Median Nerve Excision on Sciatic Functional Index in Rat: An Applicable Animal Model for Autologous Nerve Grafting. JOURNAL OF RECONSTRUCTIVE MICROSURGERY. 2011 Jan;27(1):5-10
  • Khodarahmi I, Mobasheri H, Firouzi M.The effect of 2.1 T static magnetic field on astrocyte viability and morphology. Magn Reson Imaging. 2010 Jul;28(6):903-9.
  • Vafa Rahimi-Movaghar;Atefeh Yazdi;Mehrbod Karimi;Mehdi Mohammadi;Masoumeh Firouzi;Laila Oryadi Zanjani;Mohammad Hosein Nabian. effect of decompression on complete spinal cord injury in Rats .international journal of neuroscience, 2008, 118(10)1359-1373
  • Hooshang Saberi, Pouria Moshayedi,Hamid-Reza Aghayan ,Babak Arjmand,Seyed-Kazem Hosseini,Seyed-Hassan Emami_Razavi,Vafa Rahimi-Movaghar, Mohsin Raza Masoumeh Firouzi.Treatment of chronic thoracic spinal cord injury patients with autologous Schwann cell transplantation:An interim report on safety considerations and possible outcomes. Neurosci Lett. 2008 Sep 26;443(1):46-50.
  • Masoumeh Firouzi, Pouria Moshayedi, Hooshang Saberi, Hamid Mobasheri, Farid Abolhassani, Issa Jahanzad, Mohsin Raza. Transplantation of schwann cells to subarachnoid space induces repair in contused rat spinal cord. Neurosci Lett. 2006 Jul 10; 402(1-2):66-70.
  • Bahman Yazdi-Samadi,Ali Masoudi-Nejad,Syrous Abd-Mishani,Mohamad Nabi Sarboloki,Maesumeh Firuzi Quantitative study of seed storage protein (HMW-GS) in Wheat Using Electrophoresis and Laser Scanning Densitometry.physio.mol.biol.plants.2001:7;61-66.
  • Sabouni F, Firouzi M, Taghikhani M, Ziaee AA, Semnanian S. Neurite outgrowth of dorsal root ganglia is delayed and arrested by aspirin. Biochem Biophys Res Commun. 1998 Jul 9; 248(1):165-7.
  •  Meisami E, Firoozi M. Acetylcholinesterase activity in the developing olfactory bulb: a biochemical study on normal maturation and the influence of peripheral and central connections. Brain Res. 1985 Jul; 353(1):115-24.
 

National Paper

  • Masoumeh Firouzi. Multiple Functions of the P75 Neurotrophin Receptor in the Nervous System. Zahedan J Res Med Sci 2012 Aug; 14(6): 1-5
  • Reza Erfanian; Masoumeh Firouzi, Mohammad Hosein Nabian; Masoud Darvishzadeh, Leila Oriadi Zanjani, Shayan abdollahzadegan, Reza Shahryar Kamrani..Comparison of Rat posterior Tibial nerve repair with suture and single donor human fibrin adhesive. Iranian Journal of Orthopedic Surgery .winter 2010,volum 8,nomber1,1-8 
  • Kamrani R. Sh., Firouzi M., Nabian M. H., Oriadi Zanjani L., Shaahrezaee M.,     Peripheral Nerve Graft in Severe Scar Tissue (Comparison of One and Two Stage Nerve Graft Iranian Journals of Orthopedic Surgery, 2006 summer Vol 4.number 4,1-7
  • Firouzi M, Sabouni F, Ziaee AA, Taghikhani M. Collagen as Adherent Substratum and Inducer of Dorsal Root Ganglia (DRG) Outgrowth. Iran Biomed .Iranian Biomedical Journal . 2004 April ;,8(2)101-105.  
  • Firouzi M. Microglia: Immunity and Inflammation of Central Nervous System. J Iran Pediat Assoc. 2003; May: 399-404
  • Firouzi M. The Effects of Nerve Growth Factor on Myelinatioon of Regenerated Fibers in Rat. Acta Medica Iranica. 2003; 41(3): 183-187.
  • Firouzi M, Sabouni F. Hippocampal Cell Culture without Growth and Adhesive Factors. J Sci Univ Tehran. 2002; 2: 193-203.
  • Sabouni F, Firouzi M. Role of Aspirin in the Neurite Degeneration and Apoptotic Cell Death of Hippocampal Cell Culture. Iran Biomed. 2002; 4(4): 150-156.
  • Firouzi M, Sabouni F. Schwann Cell Culture without Inhibitory Factors. Daneshvar. 2000; 30: 71-77.

 
Congresses and Meetings
 
International
  • 2011   Effects of p75NTR siRNA in Schwann cell morphology and migration. Masoumeh Firouzi,F. Sabouni,A.deezagi,Z.H.Pirbasti,M.Akbari,V.Rahimi-Movaghar.36th FEBS 2011.Torino.
  • 2010  Effects of number of stitches on nerve repair: Functional, mechanical and morphometric study using the tibial nerve of rats. Reza Erfanian Masoumeh Firouzi, Mohammad Hosein Nabian, Masoud Darvishzadeh, Leila Oriadi Zanjani, Shayan abdollahzadegan, Reza Shahryar Kamrani. 11th IFSSH  2010, Korea.
  • 2010  Comparison of suture with modified fibrin adhesive derived from single donor human on rat tibial nerve primary repair. Reza Erfanian Masoumeh Firouzi, Mohammad Hosein Nabian,  Masoud Darvishzadeh, Leila Oriadi Zanjani, Shayan abdollahzadegan, Reza Shahryar Kamrani. 11th IFSSH  2010, Korea.
  • 2008 Effect of bilateral median nerve excision on sciatic functional index in rat: an applicable animal model for autologous nerve grafting. Mohammad Hosein Nabian, Mehdi Nadji-Tehrani, Leila Oryadi Zanjani, Reza Shahryar Kamrani, Vafa Rahimi-Movaghar, Masoumeh Firouzi. Eurohand 2008.
  • 2008   Scar tissue reproducing model around the sciatic nerv of rat,  M. Firouzi,              R. S. Kamrani, L. Oriadi Zanjani , M. H. Nabian,, M. Nategh. The FEBS Journal.                           Volume 275, 28 June – 3 July 2008, Athens, Greece.  
  • 2007   Schwann cells for Spinal Cord Repair, Firouzi M., 1th interNational genomics & biotechnology:Congress of Iran, Tehran, Iran.
  • 2007  Molecular Targets to Promote Central Nervous System Regeneration, Firouzi M., Irans 1th International Conference on Biomaterials, Biomaterials Research Center (BRC), University of Tehran, Tehran, Iran.
  • 2006  Caloric Restriction Improves Motor Performance in Rodent Model of Spinal cord Injury, Ntegh M., Moshayedi P., Zanjani L., Firouzi M., Raza M., 5th Federation of European Neurosicence Societies (FENS) Forum, Vienna, Austria. 
  • 2006       A Novel route for Transparent Therapy of Injured Spinal Cord: Tracing Subarachnoid Transplanted Cells of Neonatal Spinal Cord, Moshayedi P, Firouzi M., Saberi H., Mobasheri H., 5th Federation of European Neurosicence Societies (FENS) Forum, Vienna, Austria. 
  • 2004 Effective Transplantation Method in Cell Transplant Therapy in Injured Spinal Cord of Rat: Intramedullary vs. Subarachnoid. P Moshayedi, M Firouzi, H Saberi, H Mobasheri, F Abolhassani, MA Oghabian, 4th Federation of European Neurosicence Societies (FENS) Forum, Lisbon, Portugal.
  • 2004 Effects of Schwann Cell Transplantation on Recovery of Spinal Cord Injury of Rat: A Remedy for Spinal Cord Injuries. M Firouzi, P Moshayedi, H Saberi, H Mobasheri, F Abolhassani, MA Oghabian, 4th Federation of European Neurosicence Societies (FENS) Forum, Lisbon, Portugal.
  • 2004 A Clinically Oriented Experiment on Effect of Mixed Culture of Neonate Spinal Cord Transplantation on Recovery of Spinal Cord Injury. M Firouzi, P Moshayedi, H Saberi, H Mobasheri, F Abolhassani, MA Oghabian, 2nd Symposium of Federation of Asian Oceanic Neuroscience Societies (FAONS), Tehran, Iran.
  • 2004 Effects of Crocin (a derivative of Crocus Sativus L.) on Neural Development and Regeneration of Rat: invivo and invitro Study. M Firouzi, P Moshayedi, F Sabouni, Kh Parsa, M Keshavarz, 2nd Symposium of Federation of Asian Oceanic Neuroscience Societies (FAONS), Tehran, Iran.
  • 2002 Effects of Nerve Growth Factor on Myelination of Regenerated Nerve.Firouzi M., 1st International Conference on Cell Growth and Gene Therapy. Isfahan, Iran.
  • 2002 Preparative Culture pof Pure Schwann Cells: Use in Neural Repair. Firouzi M.,  1st International Conference on Cell Growth and Gene Therapy. Isfahan, Iran.
 

 
National
  • 2010 Suggestion of a modified method for preparation of fibrin adhesive by ethanol precipitation. Reza Erfanian Masoumeh Firouzi, Masoud Darvishzadeh. International biology congress, Mashhad, Iran.
  • 2007 Axon Growth and Guidance: The Involved Mechanism and Physical Approches,  Shafeghat N., Goliaei B., Firouzi M., 8th Iran Biophysical Chemistry Conference, University of Sistan Balouchestan, Iran
  • 2006  Potential of Molecular and Immunoassay Techniques for Rapid Detecting Salmonella in Foods, Shahsavandi Sh., Ebrahimi M. M., Firouzi M., Akhavizadegan M. A., 8th National Congress of Microbiology, Isfehan, Iran.
  • 2004 Microglia as Potential Source for Neuron, Astrocyte and Oligonendrocyte. 2nd Congress on Applied Biology, Mashahd, Iran.
  • 2004 Effects of Adhesion Molecules on Astrocyte-Oligodendrocyte Interaction and Oligodendrocyte Precursor Migration. P Moshayedi, 2nd Congress on Applied Biology, Mashhad, Iran.
  • 2004 Stem Cell Isolation from Hair Follicle. 7th National Congress of Biochemistry, Ahvaz, Iran.
  • 2004 Olfactory Ensheathing Glia Culture: A New Promise for Spinal Cord Injuries. 7th National Congress of Biochemistry, Ahvaz, Iran.
  • 2003 Cultue of Progenitor Cells form Mixed Culture of Glial Cells. 1st Congress on Cellular and Developmental Biology, Tehran, Iran.
  • 2003 Different Methods for Microglia Purification from Rat Brain Cortex. P Moshayedi, 1st National Congress on Biotechnology, Mashahd, Iran.
  • 2003 Effects of GM-CSF on Microglia Cultue and Duplication. 16th Congress of Physiology and Pharmacology, Tehran, Iran.
  • 2003 Culture of Schwann Cells from Adult Diabetic Peripheral Nerve. 16th Congress of Physiology and Pharmacology, Ahvaz, Iran.
  • 2002 Neurite Elongation is Stimulated by Crocin (a Derivative of Crocus Sativus L.). 2nd Iranian Congress of Neuroscience, Tehran, Iran.
  • 2002 Microglia: Culture, Purification and Morpholocal-Physiological Evaluations. 2nd Iranian Congress of Neuroscience, Tehran, Iran.
  • 2002 Culture and Purification of Astroctes Type I&II from Rat Brain Cortex. 2nd Iranian Congress of Neuroscience, Tehran, Iran.
  • 1999 Effect of Thermal Shock on Pure Culture of Schwnn Cells. 6th National Congress of Biochemistry, Isfahan, Iran.
  • 1999 Culture and Purification of Oligodendrocyte Precursors by Vibration and Pippeting. 6th National Congress of Biochemistry, Isfahan, Iran. 
  • 1998 Effects of Aspirin on Neurite Degeneration and Apoptosis of Hippocampal Neurons in vitro. 1st Congress of Biochemistry and Biophysics, Tehran, Iran.
  • 1998 Effects of Neurotrophins on Pain. 1st Annual Congress of Pain, Tehran, Iran.
  • 1997 Isolation of βNGF from 7SNGF Bioassay. 16th Congress of Physiology and Pharmacology, Tehran, Iran.
  • 1997 Effects of Collagen as a Substratum and Outgrowth Promoter. 16th Congress of Physiology and Pharmacology, Tehran, Iran. 
  • 1997 Apoptosis-Preventive Effects of NGF in Sciatic Nerve. 16th Congress of Physiology and Pharmacology, Tehran, Iran.
  • 1997 Effect of Aspirin on Dorsal Root Ganglia. 5th National Congress of Biochemistry, Oroumieh, Iran.
  • 1996 Effect of Aspirin on Chick's Dorsal Root Ganglia: Mechanisms Involved. 7th National Congress on Biology, Isfahan, Iran. 
  • 1995 Neurite Outgrowth in Ciliary Ganglia of Chick's Embryo. 1st Congress on Zoology, Tehran, Iran.
  • 1995 Effect of NGF on Nerve Repair: in vitro Study. 13th Congress of Physiology and Pharmacology, Isfahan, Iran.
  • 1995 Schwann Cell Culture Derived from Sciatic Nerve. 4th National Congress on Biochemistry and Lab Sciences, Babol, Iran. 
  • 1995 Identifying Motor-Sensory Nerve Fibers Utilizing Histochemical Techniques. 4th National Congress on Biochemistry and Lab Sciences, Babol, Iran.
  • 1995 Effects of NGF on Sciatic Nerve Repair. 4th National Congress on Biochemistry and Lab Sciences, Babol, Iran.
  • 1995 Hippocampal Neuron Culture. 4th National Congress on Biochemistry and Lab Sciences, Babol, Iran. 
  • 1994 Genetic Evaluations of Iranian Wheat Using Electrophoresis and Multi-Parameter Statistical Analysis. 4th Congress on Agriculture, Isfahan, Iran.
  • 1994 Qualtitative Diversoty of Non-Enzymatic Proteins of Wheat Regarding HMW & LMW Glutenin. 4th Congress on Agriculture, Isfahan, Iran.
  • 1994 Comparison of HMW vs. LMW Glutenin. 4th Congress on Agriculture, Isfahan, Iran.
  • 1993 Effects of NGF on Cell Culture. 3rd National Congress on Biochemistry and Lab Sciences, Tabriz, Iran.
  • 1993 Effects of NGF on Chick Ganglia Culture. 3rd National Congress on Biochemistry and Lab Sciences, Tabriz, Iran.
  • 1993 NGF Extraction and the Effects on the Neuronal Ganglia. 4th National Congress on Biology, Tehran, Iran.
  • 1993 Methods for Nerve Growth Factor Extraction. Congress on Medical Biochemistry, Tehran, Iran.
  • 1993 Effects of Nerve Growth Factor on Cell Culture. Congress on Medical Biochemistry, Tehran, Iran.
  • 1993 Effects of Nerve Growth Factor on Neural Cell Culture. 13th Congress of Physiology and Pharmacology, Tehran, Iran.
  • 1992 Genetic Classification of Iranian Wheat Using Protein Electrophoresis. 3rd Congress on Agriculture, Tabriz, Iran.
  • 1992 Genetic Effects and Genetic Variance Constituents in Electrophoresis of Non-Enzymatic Endosperm Proteins. 3rd Congress on Agriculture, Tabriz, Iran.
 

 
Book Title     
  • 2007      Introduction to biomaterial; chapter 12.   (University of Tehran Press)
 
  • 2013       pain
 

 
Iran Patent 42055
2007      New technique of Schwann Cell Culture without Using of Adhesion and Growth Factors to Use in Cell Therapy in Different Human Nerve Diseases, Firouzi M., Iran Patent 42055.
 

 
Thesis:
 
2009          Observer in MD thesis entitled "Effect of bilateral median nerve excision on sciatic functional index in rat: an applicable animal model for autologous nerve grafting. 
 
2009         Observer in MD thesis entitled "Peripheral Nerve Graft in Severe Scar Tissue (Comparison of One and Two Stage Nerve Graft)".
 
2006        Observer in MD thesis entitled "Effect of Schwann cell transplantation to  subarachnoid space in contused rat spinal cord: electron microscopy and  immunohistochemistry evaluations ".
 
2004     Consultant in MSc Thesis entitled "Membrane fusion /repair in nerve cells: A biophysical application in spinal cord injuries regeneration".
 
2000     Observer in BSc Thesis entitled "Tissue Engineering".
 
2000     Observer in BSc Thesis entitled "Stem Cells".
 
1997     Consultant in PhD Thesis Entitled "Effects of NSAID Drugs on Neural Cell Apoptosis".
 
1996     Observer in BSc Thesis entitled "Collagen Extraction".
 
1996      Observer in BSc Thesis entitled "Nerve Growth Factor Extraction".
 
1995      Consultant in MSc Thesis entitled "Effects of Nerve Growth Factor on Cell Growth and Differentiation".
 
1994      Consultant in MSc Thesis entitled "Biochemical and Genetic Investigation on Non-Enzymatic Proteins of Parent Wheat and Comparison with Iranian Wheat".
 
1989      Consultant in MSc Thesis entitled "Effects of Bio-Oxidants on Blood Brain Barrier".