Dr. Mojtaba Bagheri Dr. Mojtaba Bagheri

 

                                                     

Mojtaba Bagheri

Assistant Professor of Biochemistry Institute of Biochemistry and Biophysics (IBB), University of Tehran
Tel:  (+98)-21-66969255, (+98)-21-61113452
Fax: (+98)-21-66404680 
E-mail: mojtabagheri@ut.ac.ir 
Web page: ibb.ut.ac.ir/~bagheri

ORCID 

                                                                                                                                                                                        

CV CV

 

                                        

 

Education

 
 
Position: Assistant Professor of Biochemistry  
 
Contact Info
Peptide Chemistry Laboratory, Institute of Biochemistry and Biophysics, University of Tehran, 16 Azar Street, 1417614335 Tehran, Iran,
P.O. Box: 13145-1365.
 
E-mail: mojtabagheri@ut.ac.ir
 
Office: Tel:  (+98)-21-66969255, (+98)-21-61113452
           Fax: (+98)-21-66404680 
 
 
November 2010 – January 2012 Postdoctoral Research Fellow
Institute of Pharmaceutical Biotechnology / University of Saarland / Saarbrücken, Germany
October 2006 – October 2010 PhD
Department of Biology, Chemistry and Pharmacy / FreieUniversität
Berlin / Berlin, Germany
September 2002 – September 2004 MSc
Department of Chemistry/ Sharif University of Technology / Tehran, Iran
September 1998 – July 2002 BSc
Department of Chemistry / Shiraz University / Shiraz, Iran
 
CURRENT POSITION
November 2012 – Present Assistant Professor
Institute of Biochemistry and Biophysics / Department of
Biochemistry, University of Tehran / Tehran, Iran
 

 

 
FUNDING 
June 2013 – September 2015 Institute of Biochemistry and Biophysics / Department of Biochemistry, University of Tehran / Tehran, Iran
Research Grant Funding for the project entitled: Design, Synthesis and Evaluation of Activities of Trypsin-Resistant Antimicrobial Peptides to Develop Drugs for Treatment of Infections Caused by Bacterial Superbugs, received from the Iran National Science Foundation
 

Publications Publications

 
1.   Dinh Thuy Duong, Shalini Singh, Mojtaba Bagheri,  Artur Schmidtchen,  and Martin Malmsten. 2016. Pronounced peptide selectivity for melanoma through tryptophan end-tagging. Scientific Reports, in revision
2.   Mojtaba Bagheri,   Shima Arasteh,   Evan F. Haney,   Robert E. W. Hancock.
2016. Tryptic stability of synthetic bactenecin derivatives is determined by the side chain length of cationic residues and the peptide conformation.  Journal of Medicinal Chemistry, 59:ASAP
3. MojtabaBagheri.   2015.   Cationic   antimicrobial   peptides   (AMPs): thermodynamic characterization of peptide-lipid interactions and biological efficacy of surface-tethered peptides. ChemistryOpen, 4:389-393.
4.   Saeed Yousefinejad,  Mojtaba Bagheri,  Ali Akbar Moosavi-Movahedi.  2015.
Quantitative sequence-activity modeling of antimicrobial hexapeptides using a segmented principal component strategy: an approach to describe and predict activities    of   peptide   drugs   containing    L/D   and   unnatural    residues. Amino Acids, 47:125-134. (# citations: 4)
5.   Mojtaba Bagheri, Shima Arasteh, Evan F. Haney, and Robert E. W. Hancock.
2014.  Structural  and  thermodynamic   characterization   of  trypsin-resistant cathelicidin   derived   antimicrobial   peptides.    Journal   of   Peptide Science,
20:(S1):70–70.
6.   Mojtaba Bag heri, Michael Beyermann, and Margitta Dathe. 2012. The mode of action of cationic antimicrobial peptide defines the tethering position and the efficacy    of   biocidal    surface.    Bioconjugate    Chemistry,    23:66-74. (# citations: 25)
7.   Mojtaba Bagheri, Sandro Keller, and Margitta Dathe. 2011. Interaction of W- substituted analogs of cyclo-RRRWFR with bacterial lipopolysaccarides:  The role of aromatic  cluster  in antimicrobial  activity.  Antimicrobial Agents  and Chemotherapy, 55:788−797. (# citations: 16)
8.   Christof  Junkes,  Richard  D.  Harvey,  Kenneth  D.  Bruce,  Rudolf  Dölling, Mojtaba Bagh eri, and Margitta Dathe. 2011. Cyclic antimicrobial R-,W-rich peptides: the role of peptide structure and E. coli inner and outer membranes in activity and the mode of action.  European Biophysics Journal, 40: 515−528. (# citations: 24)
9.   Mojtaba Bagh   eri, Michael Beyermann, and Margitta Dathe. 2009.
Immobilization reduces the activity of surface-bound cationic antimicrobial peptides with no influence  upon the activity spectrum.  Antimicrobial Agents and Chemotherapy, 53:1132−1141. (# citations: 101)
10. Mojtaba Bagheri,  Michael Beyermann, and Margitta Dathe. 2008. Surface- bound cationic antimicrobial peptides: The effect of immobilization upon the activity   spectrum   and  the  mode  of  action.   Journal   of  Peptide Science,
14:(S1):5–5.
11. Mojtaba B agheri, Najmedin Azizi, and M. Reza Saidi. 2005. An intriguing effect  of  lithium  perchlorate  dispersed  on  silica  gel  in  the  bromination  of aromatic compounds by N-bromosuccinimide.  Canadian Journal of Chemistry,
83:146−149.(# citations: 14)
12. Firouz Matloubi  Moghaddam,  Hassan Zali Boeini,  Mojtaba Bagheri,  Peter Rüedi,  and  Anthony  Linden.  2005.  Highly  efficient  and  versatile  one-pot synthesis  of new thiophenelyidene  compounds.  Journal of Sulfur Chemistry,
26:245−250. (# citations

 
1.   Shima  Arasteh,  Mojtaba Bagheri ,  and  Bahram  Goliaei.  2014.  Membrane selectivity of small cyclic antimicrobial hexapeptides studied by molecular dynamics simulations. Peptide 2014 - 33EPS Proceedings. pp. 306−307.
2.   Mojtaba Bagheri. May 2013. Inhibition of Bacterial Biofilms by
Antimicrobial  Peptides:  Take  a  Glance  at  the  Parameters  Affecting  the Efficacy of Surface-Tethered Antimicrobial Peptides. Proceedings of the 1st International life science conference & 12th Iran biophysical chemistry conference at Tabriz. Tabriz University of Medical Sciences (Iran). pp. 2–2.
3.   Shima Arasteh, Mojtaba Bagheri, and Bahram Goliaei. May 2013.
Molecular dynamics simulation studies of antimicrobial cyclo-RRRWFW and its analogs in water and POPC bilayers. Proceedings of the 1st  International life  science  conference  &  12th   Iran  biophysical  chemistry  conference  at Tabriz. Tabriz University of Medical Sciences (Iran). pp. 432–432.
4.   Saeed Yousefinejad, Mojtaba Bagheri, Ali Akbar Moosavi-Movahedi.
May 2013.  Quantitative  sequence-activity  modeling  of  linear  hexapeptide antibiotics: an approach for the prediction and description of antifungal activitys. Proceedings  of the 1st  International  life science conference  & 12th Iran biophysical chemistry conference at Tabriz. Tabriz University of Medical Sciences (Iran). pp. 423–423.
5.   Mojtaba B agheri.  June 2012.   Interaction  of  cationic  peptide  drugs  with bacteria and lipid bilayers: short R-, W-rich hexapeptides as a case study. Proceedings of the 1st International & 11th Iran Conference on Biophysical Chemistry  at  Ardabil,  Ardabil  University  of  Medical  Sciences  (Iran).  pp.
A114−A114 (Abstract # 268).
6.   Mojtaba B agheri,  Sandro  Keller,  and  Margitta  Dathe.  February 2010.
Interactions  of  W-substituted  cyclo-RRRWFW  analogues  with  lipid membranes  studied  by isothermal  titration  calorimetry.  Proceedings  of the 12th Iberian  peptide  meeting  at Lisbon,  University  of Lisbon  (Portugal). pp.
50-50.
7.   Mojtaba  B agheri,  Michael  Beyermann, and Margitta  Dathe. 2 008.  Surface­ bound cationic antimicrobial peptides: The effect of immobilization upon the activity spectrum and the mode of action. Peptides  2008 - 30EPS Proceedings. pp. 208-209.
 

 

 
1.   Mojtaba Bagheri, and Robert E. W. Hancock. 2016. High performance liquid chromatography and mass spectrometry-based design of proteolytically stable antimicrobial peptides. In Antimicrobial Peptides: Methods and Protocols; Methods  in Molecular  Biology,  in rev ision.  Ed. Hansen, P. R. The Humana Press Inc., Springer Science, New York.
 
2.   Shima Arasteh, and Mojtaba Bagheri. 2016. Molecular dynamics simulation and analysis of the antimicrobial peptides-lipid bilayers interactions. In Antimicrobial   Peptides:   Methods   and   Protocols;   Methods   in   Molecular Biology,  in rev ision.  Ed. Hansen, P. R.  The  Humana  Press  Inc.,  Springer Science, New York.
 
3.   Mojtaba Ba gheri. 20 10.  Synthesis  and  thermodynamic  characterization  of small   cyclic   antimicrobial   arginine   and   tryptophan   rich   peptides   with selectivity for Gram-negative bacteria.In Antimicrobial Peptides: Methods and Protocols;  Methods  in  Molecular  Biology,  Vol. 618.  Eds. Giuliani, A.,  and Rinaldi, A. C. The Humana Press Inc., Springer Science, New York. 87−109. (# citations: 3)
 

 
SUPERVISING AND MENTORING ACTIVITIES 
November 2012 – Present 1 PhD /4 Master Students
Institute of Biochemistry and Biophysics / Department of Biochemistry, University of Tehran / Tehran, Iran
 
MEMBERSHIPS OF SCIENTIFIC SOCIETIES
September 2008 – Present Member, European Peptide Society
 
ORGANISATION OF SCIENTIFIC MEETINGS
18/02/2014 Symposium Chair, 1st Iranian Symposium on Biomimetic Science and Technology / Institute of Biochemistry and Biophysics / University of Tehran, number of participants 70
 
 
 

 

PRIZES AND AWARDS
 
June 2014 – September 2014 Pharmaceutical Physical Chemistry / Department of Pharmacy /Biomedical Centre (BMC), Uppsala University / Uppsala, Sweden 
Wood-Whelan Research Fellowships, Award received from the International Union of Biochemistry and Molecular Biology (IUBMB)
 
December 2013 Clinical Research Centre (MD11) / National University of Singapore / Singapore
Travel Fellowship, 23rd of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) conference, Award received from FAOBMB
 
February 2013 Institute of Biochemistry and Biophysics / Department of Biochemistry, University of Tehran / Tehran, Iran 
Kazemi Ashtiani Award, Allocated to Young Elite Faculty Members of National University, Award received from the Iran's National Elites Foundation
 
September 2008 ONGREX / Blue & White Conferences Oy, Helsinki, Finland Travel Fellowship, 30th European Peptide symposium, Award received from the European Peptide Society July 2002 7th Chemistry Olympiad of University Students, 23-26
 
July 2002, Ardabil, Iran Recipient of the Gold Medal, Award received from the National Organization for Educational esting
 
September 2004 – September 2005 Department of Chemistry/ Sharif University of
Technology / Tehran, Iran
Fellowships for outstanding research student, Award received from Sharif University of Technology
 

 
TEACHING ACTIVITIES
September 2013 – Present  Full-time  course teaching–Structures and Functions of Peptides and Peptidomimetics, University of Tehran / Institute  of Biochemistry and Biophysics /Tehran, Iran
February 2014 – Present   Part-time course  teaching–Methods in Biochemistry; NMR, University of Tehran / Institute of Biochemistry and Biophysics / Tehran, Iran
February 2016 – Present   Full-time course teaching – Biophysics, University of Tehran / Faculty of Science / Department of Biology / Tehran, Iran